![]() ![]() VisualizeMED is your opportunity to gain the kind of firsthand knowledge that’s essential to making the technology work for you-it’s where you can hear perspectives from experts, see solutions in action, or find your next potential opportunity to collaborate. Applicants: Massachusetts Institute of Technology, The Brigham and Womens Hospital, Inc. Inspired by an ancient technology, engineers design a sensor that. In some embodiments, the structures and systems described herein comprise one or more materials configured for high levels of active substances (e.g., a therapeutic agent) loading, high active substance and/or structure stability in acidic environments, mechanical flexibility and strength in an internal orifice (e.g., gastric cavity), easy passage through the GI tract until delivery to at a desired internal orifice (e.g., gastric cavity), and/or rapid dissolution/degradation in a physiological environment (e.g., intestinal environment) and/or in response to a chemical stimulant (e.It can be difficult to know how and when to leverage modeling and simulation in medicine. A simple diagnostic tool for gastrointestinal disorders. The residence structure may be, in some cases, a gastric residence structure. Certain embodiments comprise administering (e.g., orally) a residence structure to a subject (e.g., a patient) such that the residence structure is retained at a location internal to the subject for a particular amount of time (e.g., at least about 24 hours) before being released. In some embodiments, each tissue-interfacing component may comprise an electrically-conductive portion configured for electrical communication with tissue and an insulative portion configured to not be in electrical communication with tissue.Ībstract: Residence structures, systems, and related methods are generally provided. I studied and play oboe, pianoforte, synthesizers, guitars and vocals. My skills are for composing (both music & lyrics) & mixing. Traverso, Karl Van Tassel (1925) Career Development Professor, together with his team identified unmet. Earlier this year, as the enormity of the pandemic became clear, he swung into action. Previous affiliations of Giovanni Traverso include Harvard University & Massachusetts Institute of Technology. As both a biomedical engineer and physician, Giovanni Traverso is uniquely positioned to tackle the challenges associated with Covid-19. The author has an hindex of 35, co-authored 120 publication(s) receiving 8776 citation(s). The author has contributed to research in topic(s): Drug delivery & Inflammatory bowel disease. ![]() ![]() In certain embodiments, the self-righting article a tissuel0 interfacing components. Hello everybody, I am a music producer based in Europe, north-west of italy. Giovanni Traverso is a academic researcher from Brigham and Womens Hospital. In some embodiments, the self-righting article may have a particular shape and/or distribution of density (or mass) which, for example, enables the self-righting behavior of the article. The self-righting articles described herein may comprise one 5 or more tissue engaging surfaces configured to engage (e.g., interface with, inject into, anchor) with a surface (e.g., a surface of a tissue of a subject). ![]() In some embodiments, the self-righting article may be configured such that the article may orient itself relative to a surface (e.g., a surface of a tissue of a subject). Advantageously, in some embodiments, the reduction of volume required to deliver the required API dose as compared to a liquid formulation permits the creation of solid needle delivery systems for a wide variety of drugs in a variety of places/tissues (e.g., tongue, GI mucosal tissue, skin) and/or reduces and/or eliminates the application of an external force in order to inject a drug solution through the small opening in the needle.Ībstract: Self-righting articles, such as self-righting capsules for administration to a subject, are generally provided. Such tissue-interfacing components may be useful for delivery of API doses e.g., to a subject. Giovanni Traverso is an Assistant Professor in the Department of Mechanical Engineering at the Massachusetts Institute of Technology (MIT) and also a. In some embodiments, the component (e.g., a tissue interfacing component) comprises a solid therapeutic agent (e.g., a solid API) and a supporting material (e.g., a binder such as a polymer) such that the solid therapeutic agent is present in the component in an amount of greater than or equal to 10 wt % versus the total weight of the tissue interfacing component. Abstract: Components with relatively high loading of active pharmaceutical ingredients (e.g., drugs), are generally provided. ![]()
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